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    2024

  1. Ancestral Genomic Functional Differences in Oligodendroglia: Implications for Alzheimer's Disease

    Ramirez, AM; Bertholim-Nasciben, L; Moura, S; Coombs, LE; Rajabli, F; DeRosa, BA; Whitehead, PG; Adams, LD; Starks, TD; Mena, P; Illannes-Manrique, M; Tejada, SJ; Byrd, GS; Caban-Holt, A; Cuccaro, M; McInerney, K; Cornejo-Olivas, M; Feliciano-Astacio, B; Wang, L; Robayo, MC; Xu, W; Jin, F; Pericak-Vance, MA; Griswold, AJ; Dykxhoorn, DM; Young, JI; Vance, JM;
    2024;  
    Research Square;  
  2. Integrated multimodal cell atlas of Alzheimer's disease

    Gabitto, MI; Travaglini, KJ; Rachleff, VM; Kaplan, ES; Long, B; Ariza, J; Ding, Y; Mahoney, JT; Dee, N; Goldy, J; Melief, EJ; Agrawal, A; Kana, O; Zhen, X; Barlow, ST; Brouner, K; Campos, J; Campos, J; Carr, AJ; Casper, T; Chakrabarty, R; Clark, M; Cool, J; Dalley, R; Darvas, M; Ding, S; Dolbeare, T; Egdorf, T; Esposito, L; Ferrer, R; Fleckenstein, LE; Gala, R; Gary, A; Gelfand, E; Gloe, J; Guilford, N; Guzman, J; Hirschstein, D; Ho, W; Hupp, M; Jarsky, T; Johansen, N; Kalmbach, BE; Keene, LM; Khawand, S; Kilgore, MD; Kirkland, A; Kunst, M; Lee, BR; Leytze, M; Mac Donald, CL; Malone, J; Maltzer, Z; Martin, N; McCue, R; McMillen, D; Mena, G; Meyerdierks, E; Meyers, KP; Mollenkopf, T; Montine, M; Nolan, AL; Nyhus, JK; Olsen, PA; Pacleb, M; Pagan, CM; Peña, N; Pham, T; Pom, CA; Postupna, N; Rimorin, C; Ruiz, A; Saldi, GA; Schantz, AM; Shapovalova, NV; Sorensen, SA; Staats, B; Sullivan, M; Sunkin, SM; Thompson, C; Tieu, M; Ting, JT; Torkelson, A; Tran, T; Valera Cuevas, NJ; Walling-Bell, S; Wang, M; Waters, J; Wilson, AM; Xiao, M; Haynor, D; Gatto, NM; Jayadev, S; Mufti, S; Ng, L; Mukherjee, S; Crane, PK; Latimer, CS; Levi, BP; Smith, KA; Close, JL; Miller, JA; Hodge, RD; Larson, EB; Grabowski, TJ; Hawrylycz, M; Keene, CD; Lein, ES;
    2024;  
    Nature Neuroscience;  
    Volume: 27;  
    Issue: 12;  
  3. Association of common and rare variants with Alzheimer's disease in more than 13,000 diverse individuals with whole-genome sequencing from the Alzheimer's Disease Sequencing Project

    Lee, W; Choi, SH; Shea, MG; Cheng, P; Dombroski, BA; Pitsillides, AN; Heard-Costa, NL; Wang, H; Bulekova, K; Kuzma, AB; Leung, YY; Farrell, JJ; Lin, H; Kunkle, BW; Naj, A; Blue, EE; Nusetor, F; Wang, D; Boerwinkle, E; Bush, WS; Zhang, X; De Jager, PL; Dupuis, J; Farrer, LA; Fornage, M; Martin, E; Pericak-Vance, M; Seshadri, S; Wijsman, EM; Wang, L; Alzheimer's Disease Sequencing Project; Schellenberg, GD; Destefano, AL; Haines, JL; Peloso, GM;
    2024;  
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association;  
    Volume: 20;  
    Issue: 12;  
  4. Proteogenomic analysis of human cerebrospinal fluid identifies neurologically relevant regulation and implicates causal proteins for Alzheimer's disease

    Western, D; Timsina, J; Wang, L; Wang, C; Yang, C; Phillips, B; Wang, Y; Liu, M; Ali, M; Beric, A; Gorijala, P; Kohlfeld, P; Budde, J; Levey, AI; Morris, JC; Perrin, RJ; Ruiz, A; Marquié, M; Boada, M; de Rojas, I; Rutledge, J; Oh, H; Wilson, EN; Le Guen, Y; Reus, LM; Tijms, B; Visser, PJ; van der Lee, SJ; Pijnenburg, YAL; Teunissen, CE; Del Campo Milan, M; Alvarez, I; Aguilar, M; Dominantly Inherited Alzheimer Network (DIAN); Alzheimer’s Disease Neuroimaging Initiative (ADNI); Greicius, MD; Pastor, P; Pulford, DJ; Ibanez, L; Wyss-Coray, T; Sung, YJ; Cruchaga, C;
    2024;  
    Nature Genetics;  
    Volume: 56;  
    Issue: 12;  
  5. CD8+ T cells exacerbate AD-like symptoms in mouse model of amyloidosis

    Wang, X; Campbell, B; Bodogai, M; McDevitt, RA; Patrikeev, A; Gusev, F; Ragonnaud, E; Kumaraswami, K; Shirenova, S; Vardy, K; Alameh, M; Weissman, D; Ishikawa-Ankerhold, H; Okun, E; Rogaev, E; Biragyn, A;
    2024;  
    Brain, Behavior, and Immunity;  
    Volume: 122;  
  6. Missense and loss-of-function variants at GWAS loci in familial Alzheimer's disease

    Gunasekaran, TI; Reyes-Dumeyer, D; Faber, KM; Goate, A; Boeve, B; Cruchaga, C; Pericak-Vance, M; Haines, JL; Rosenberg, R; Tsuang, D; Mejia, DR; Medrano, M; Lantigua, RA; Sweet, RA; Bennett, DA; Wilson, RS; Alba, C; Dalgard, C; Foroud, T; Vardarajan, BN; Mayeux, R;
    2024;  
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association;  
    Volume: 20;  
    Issue: 11;  
  7. CSF proteomics identifies early changes in autosomal dominant Alzheimer's disease

    Shen, Y; Timsina, J; Heo, G; Beric, A; Ali, M; Wang, C; Yang, C; Wang, Y; Western, D; Liu, M; Gorijala, P; Budde, J; Do, A; Liu, H; Gordon, B; Llibre-Guerra, JJ; Joseph-Mathurin, N; Perrin, RJ; Maschi, D; Wyss-Coray, T; Pastor, P; Renton, AE; Surace, EI; Johnson, ECB; Levey, AI; Alvarez, I; Levin, J; Ringman, JM; Allegri, RF; Seyfried, N; Day, GS; Wu, Q; Fernández, MV; Tarawneh, R; McDade, E; Morris, JC; Bateman, RJ; Goate, A; Dominantly Inherited Alzheimer Network; Ibanez, L; Sung, YJ; Cruchaga, C;
    2024;  
    Cell;  
    Volume: 187;  
    Issue: 22;  
  8. Blood-derived mitochondrial DNA copy number is associated with Alzheimer disease, Alzheimer-related biomarkers and serum metabolites

    Tong, T; Zhu, C; Farrell, JJ; Khurshid, Z; Alzheimer’s Disease Sequencing Project, Alzheimer’s Disease Neuroimaging Initiative; Martin, ER; Pericak-Vance, MA; Wang, L; Bush, WS; Schellenberg, GD; Haines, JL; Qiu, WQ; Lunetta, KL; Farrer, LA; Zhang, X;
    2024;  
    Alzheimer's Research & Therapy;  
    Volume: 16;  
    Issue: 1;  
  9. Alzheimer's disease risk gene CD2AP is a dose-sensitive determinant of synaptic structure and plasticity

    Pavešković, M; De-Paula, RB; Ojelade, SA; Tantry, EK; Kochukov, MY; Bao, S; Veeraragavan, S; Garza, AR; Srivastava, S; Song, S; Fujita, M; Duong, DM; Bennett, DA; De Jager, PL; Seyfried, NT; Dickinson, ME; Heaney, JD; Arenkiel, BR; Shulman, JM;
    2024;  
    Human Molecular Genetics;  
    Volume: 33;  
    Issue: 20;  
  10. 2024;  
    Trends in Molecular Medicine;  
    Volume: 30;  
    Issue: 10;  
  11. Tau is required for glial lipid droplet formation and resistance to neuronal oxidative stress

    Goodman, LD; Ralhan, I; Li, X; Lu, S; Moulton, MJ; Park, Y; Zhao, P; Kanca, O; Ghaderpour Taleghani, ZS; Jacquemyn, J; Shulman, JM; Ando, K; Sun, K; Ioannou, MS; Bellen, HJ;
    2024;  
    Nature Neuroscience;  
    Volume: 27;  
    Issue: 10;  
  12. Cognitive resilience to Alzheimer's disease characterized by cell-type abundance

    O'Neill, N; Stein, TD; Olayinka, OA; Empawi, JA; Hu, J; Tong, T; Zhang, X; Farrer, LA;
    2024;  
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association;  
    Volume: 20;  
    Issue: 10;  
  13. A transient brain endothelial translatome response to endotoxin is associated with mild cognitive changes post-shock in young mice

    Lu, S; Di John Portela, I; Martino, N; Bossardi Ramos, R; Salinero, AE; Smith, RM; Zuloaga, KL; Adam, AP;
    2024;  
    Neuroscience;  
    Volume: 555;  
  14. 2024;  
    Aging Cell;  
    Volume: 23;  
    Issue: 9;  
  15. A genetic and proteomic comparison of key AD biomarkers across tissues

    Marsh, TW; Western, D; Timsina, J; Gorijala, P; Yang, C; Pastor, P; Liu, M; Morris, JC; Bateman, RJ; Schindler, SE; Sung, YJ; Dominantly Inherited Alzheimer Network; Cruchaga, C;
    2024;  
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association;  
    Volume: 20;  
    Issue: 9;  
  16. Advancements in APOE and dementia research: Highlights from the 2023 AAIC Advancements: APOE conference

    Kloske, CM; Belloy, ME; Blue, EE; Bowman, GR; Carrillo, MC; Chen, X; Chiba-Falek, O; Davis, AA; Paolo, GD; Garretti, F; Gate, D; Golden, LR; Heinecke, JW; Herz, J; Huang, Y; Iadecola, C; Johnson, LA; Kanekiyo, T; Karch, CM; Khvorova, A; Koppes-den Hertog, SJ; Lamb, BT; Lawler, PE; Guen, YL; Litvinchuk, A; Liu, C; Mahinrad, S; Marcora, E; Marino, C; Michaelson, DM; Miller, JJ; Morganti, JM; Narayan, PS; Naslavsky, MS; Oosthoek, M; Ramachandran, KV; Ramakrishnan, A; Raulin, A; Robert, A; Saleh, RNM; Sexton, C; Shah, N; Shue, F; Sible, IJ; Soranno, A; Strickland, MR; Tcw, J; Thierry, M; Tsai, L; Tuckey, RA; Ulrich, JD; van der Kant, R; Wang, N; Wellington, CL; Weninger, SC; Yassine, HN; Zhao, N; Bu, G; Goate, AM; Holtzman, DM;
    2024;  
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association;  
    Volume: 20;  
    Issue: 9;  
  17. 2024;  
    Environmental Health Perspectives;  
    Volume: 132;  
    Issue: 9;  
  18. 2024;  
    PLoS computational biology;  
    Volume: 20;  
    Issue: 9;  
  19. Epigenetic and genetic risk of Alzheimer disease from autopsied brains in two ethnic groups

    Ma, Y; Reyes-Dumeyer, D; Piriz, A; Recio, P; Mejia, DR; Medrano, M; Lantigua, RA; Vonsattel, JPG; Tosto, G; Teich, AF; Ciener, B; Leskinen, S; Sivakumar, S; DeTure, M; Ranjan, D; Dickson, D; Murray, M; Lee, E; Wolk, DA; Jin, L; Dugger, BN; Hiniker, A; Rissman, RA; Mayeux, R; Vardarajan, BN;
    2024;  
    Acta Neuropathologica;  
    Volume: 148;  
    Issue: 1;  
  20. Effects of high fat diet on metabolic health vary by age of menopause onset

    Salinero, AE; Venkataganesh, H; Abi-Ghanem, C; Riccio, D; Kelly, RD; Gannon, OJ; Sura, A; Brooks, HL; Zuloaga, DG; Zuloaga, KL;
    2024;  
    International Journal of Obesity (2005);  
  21. Treatment with brain specific estrogen prodrug ameliorates cognitive effects of surgical menopause in mice

    Salinero, AE; Abi-Ghanem, C; Venkataganesh, H; Sura, A; Smith, RM; Thrasher, CA; Kelly, RD; Hatcher, KM; NyBlom, V; Shamlian, V; Kyaw, N; Belanger, KM; Gannon, OJ; Stephens, SBZ; Zuloaga, DG; Zuloaga, KL;
    2024;  
    Hormones and Behavior;  
    Volume: 164;  
  22. Extended genome-wide association study employing the African genome resources panel identifies novel susceptibility loci for Alzheimer's disease in individuals of African ancestry

    Ray, NR; Kunkle, BW; Hamilton-Nelson, K; Kurup, JT; Rajabli, F; Qiao, M; Vardarajan, BN; Cosacak, MI; Kizil, C; Jean-Francois, M; Cuccaro, M; Reyes-Dumeyer, D; Cantwell, L; Kuzma, A; Vance, JM; Gao, S; Hendrie, HC; Baiyewu, O; Ogunniyi, A; Akinyemi, RO; Alzheimer's Disease Genetics Consortium; Lee, W; Martin, ER; Wang, L; Beecham, GW; Bush, WS; Xu, W; Jin, F; Wang, L; Farrer, LA; Haines, JL; Byrd, GS; Schellenberg, GD; Mayeux, R; Pericak-Vance, MA; Reitz, C;
    2024;  
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association;  
    Volume: 20;  
    Issue: 8;  
  23. Ubiquitin-Proteasome System in the Different Stages of Dominantly Inherited Alzheimer's Disease

    McDade, E; Liu, H; Bui, Q; Hassenstab, J; Gordon, B; Benzinger, T; Shen, Y; Timsina, J; Wang, L; Sung, YJ; Karch, C; Renton, A; Daniels, A; Morris, J; Xiong, C; Ibanez, L; Perrin, R; Llibre-Guerra, JJ; Day, G; Supnet-Bell, C; Xu, X; Berman, S; Chhatwal, J; Ikeuchi, T; Kasuga, K; Niimi, Y; Huey, E; Schofield, P; Brooks, W; Ryan, N; Jucker, M; Laske, C; Levin, J; Vöglein, J; Roh, JH; Lopera, F; Bateman, R; Cruchaga, C;
    2024;  
    Research Square;  
  24. High-Resolution Mass Spectrometry for Human Exposomics: Expanding Chemical Space Coverage

    Lai, Y; Koelmel, JP; Walker, DI; Price, EJ; Papazian, S; Manz, KE; Castilla-Fernández, D; Bowden, JA; Nikiforov, V; David, A; Bessonneau, V; Amer, B; Seethapathy, S; Hu, X; Lin, EZ; Jbebli, A; McNeil, BR; Barupal, D; Cerasa, M; Xie, H; Kalia, V; Nandakumar, R; Singh, R; Tian, Z; Gao, P; Zhao, Y; Froment, J; Rostkowski, P; Dubey, S; Coufalíková, K; Seličová, H; Hecht, H; Liu, S; Udhani, HH; Restituito, S; Tchou-Wong, K; Lu, K; Martin, JW; Warth, B; Godri Pollitt, KJ; Klánová, J; Fiehn, O; Metz, TO; Pennell, KD; Jones, DP; Miller, GW;
    2024;  
    Environmental Science & Technology;  
    Volume: 58;  
    Issue: 29;  
  25. European and African-specific plasma protein-QTL and metabolite-QTL analyses identify ancestry-specific T2D effector proteins and metabolites

    Cruchaga, C; Yang, C; Gorijala, P; Timsina, J; Wang, L; Liu, M; Wang, C; Brock, W; Wang, Y; Sung, YJ;
    2024;  
    Research Square;  
  26. Proteogenomics in cerebrospinal fluid and plasma reveals new biological fingerprint of cerebral small vessel disease

    Debette, S; Caro, I; Western, D; Namba, S; Sun, N; Kawaguchi, S; He, Y; Fujita, M; Roshchupkin, G; D'Aoust, T; Duperron, M; Sargurupremraj, M; Tsuchida, A; Koido, M; Ahmadi, M; Yang, C; Timsina, J; Ibanez, L; Matsuda, K; Suzuki, Y; Oda, Y; Kanai, A; Jandaghi, P; Munter, HM; Auld, D; Astafeva, I; Puerta, R; Rotter, J; Psaty, B; Bis, J; Longstreth, W; Couffinhal, T; Garcia-Gonzalez, P; Pytel, V; Marquié, M; Cano, A; Boada, M; Joliot, M; Lathrop, M; Le Grand, Q; Launer, L; Wardlaw, J; Heiman, M; Ruiz, A; Matthews, P; Seshadri, S; Fornage, M; Adams, H; Mishra, A; Trégouët, D; Okada, Y; Kellis, M; De Jager, P; Tzourio, C; Kamatani, Y; Matsuda, F; Cruchaga, C;
    2024;  
    Research Square;  
  27. Post-GWAS multiomic functional investigation of the TNIP1 locus in Alzheimer's disease highlights a potential role for GPX3

    Panyard, DJ; Reus, LM; Ali, M; Liu, J; Deming, YK; Lu, Q; Kollmorgen, G; Carboni, M; Wild, N; Visser, PJ; Bertram, L; Zetterberg, H; Blennow, K; Gobom, J; Western, D; Sung, YJ; Carlsson, CM; Johnson, SC; Asthana, S; Cruchaga, C; Tijms, BM; Engelman, CD; Snyder, MP;
    2024;  
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association;  
    Volume: 20;  
    Issue: 7;  
  28. Gliovascular transcriptional perturbations in Alzheimer's disease reveal molecular mechanisms of blood brain barrier dysfunction

    İş, Ö; Wang, X; Reddy, JS; Min, Y; Yilmaz, E; Bhattarai, P; Patel, T; Bergman, J; Quicksall, Z; Heckman, MG; Tutor-New, FQ; Can Demirdogen, B; White, L; Koga, S; Krause, V; Inoue, Y; Kanekiyo, T; Cosacak, MI; Nelson, N; Lee, AJ; Vardarajan, B; Mayeux, R; Kouri, N; Deniz, K; Carnwath, T; Oatman, SR; Lewis-Tuffin, LJ; Nguyen, T; Alzheimer’s Disease Neuroimaging Initiative; Carrasquillo, MM; Graff-Radford, J; Petersen, RC; Jr Jack, CR; Kantarci, K; Murray, ME; Nho, K; Saykin, AJ; Dickson, DW; Kizil, C; Allen, M; Ertekin-Taner, N;
    2024;  
    Nature Communications;  
    Volume: 15;  
    Issue: 1;  
  29. 2024;  
    Hormones and Behavior;  
    Volume: 162;  
  30. The 2022 symposium on dementia and brain aging in low- and middle-income countries: Highlights on research, diagnosis, care, and impact

    Kalaria, R; Maestre, G; Mahinrad, S; Acosta, DM; Akinyemi, RO; Alladi, S; Allegri, RF; Arshad, F; Babalola, DO; Baiyewu, O; Bak, TH; Bellaj, T; Brodie-Mends, DK; Carrillo, MC; Celestin, K; Damasceno, A; de Silva, RK; de Silva, R; Djibuti, M; Dreyer, AJ; Ellajosyula, R; Farombi, TH; Friedland, RP; Garza, N; Gbessemehlan, A; Georgiou, EE; Govia, I; Grinberg, LT; Guerchet, M; Gugssa, SA; Gumikiriza-Onoria, JL; Hogervorst, E; Hornberger, M; Ibanez, A; Ihara, M; Issac, TG; Jönsson, L; Karanja, WM; Lee, JH; Leroi, I; Livingston, G; Manes, FF; Mbakile-Mahlanza, L; Miller, BL; Musyimi, CW; Mutiso, VN; Nakasujja, N; Ndetei, DM; Nightingale, S; Novotni, G; Nyamayaro, P; Nyame, S; Ogeng'o, JA; Ogunniyi, A; de Oliveira, MO; Okubadejo, NU; Orrell, M; Paddick, S; Pericak-Vance, MA; Pirtosek, Z; Potocnik, FCV; Raman, R; Rizig, M; Rosselli, M; Salokhiddinov, M; Satizabal, CL; Sepulveda-Falla, D; Seshadri, S; Sexton, CE; Skoog, I; George-Hyslop, PHS; Suemoto, CK; Thapa, P; Udeh-Momoh, CT; Valcour, V; Vance, JM; Varghese, M; Vera, JH; Walker, RW; Zetterberg, H; Zewde, YZ; Ismail, O;
    2024;  
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association;  
    Volume: 20;  
    Issue: 6;  
  31. A comparative study of structural variant calling in WGS from Alzheimer's disease families

    Malamon, JS; Farrell, JJ; Xia, LC; Dombroski, BA; Das, RG; Way, J; Kuzma, AB; Valladares, O; Leung, YY; Scanlon, AJ; Lopez, IAB; Brehony, J; Worley, KC; Zhang, NR; Wang, L; Farrer, LA; Schellenberg, GD; Lee, W; Vardarajan, BN;
    2024;  
    Life Science Alliance;  
    Volume: 7;  
    Issue: 5;  
  32. TOPMed imputed genomics enhances genomic atlas of the human proteome in brain, cerebrospinal fluid, and plasma

    Yi, H; Yang, Q; Repaci, C; Lee, CM; Heo, G; Timsina, J; Gorijala, P; Yang, C; Budde, J; Wang, L; Cruchaga, C; Sung, YJ;
    2024;  
    Scientific Data;  
    Volume: 11;  
    Issue: 1;  
  33. Rare genetic variation in fibronectin 1 (FN1) protects against APOEε4 in Alzheimer's disease

    Bhattarai, P; Gunasekaran, TI; Belloy, ME; Reyes-Dumeyer, D; Jülich, D; Tayran, H; Yilmaz, E; Flaherty, D; Turgutalp, B; Sukumar, G; Alba, C; McGrath, EM; Hupalo, DN; Bacikova, D; Le Guen, Y; Lantigua, R; Medrano, M; Rivera, D; Recio, P; Nuriel, T; Ertekin-Taner, N; Teich, AF; Dickson, DW; Holley, S; Greicius, M; Dalgard, CL; Zody, M; Mayeux, R; Kizil, C; Vardarajan, BN;
    2024;  
    Acta Neuropathologica;  
    Volume: 147;  
    Issue: 1;  
  34. CSF biomarkers of immune activation and Alzheimer's disease for predicting cognitive impairment risk in the elderly

    Shue, F; White, LJ; Hendrix, R; Ulrich, J; Henson, RL; Knight, W; Martens, YA; Wang, N; Roy, B; Starling, SC; Ren, Y; Xiong, C; Asmann, YW; Syrjanen, JA; Vassilaki, M; Mielke, MM; Timsina, J; Sung, YJ; Cruchaga, C; Holtzman, DM; Bu, G; Petersen, RC; Heckman, MG; Kanekiyo, T;
    2024;  
    Science Advances;  
    Volume: 10;  
    Issue: 14;  
  35. Brain high-throughput multi-omics data reveal molecular heterogeneity in Alzheimer's disease

    Eteleeb, AM; Novotny, BC; Tarraga, CS; Sohn, C; Dhungel, E; Brase, L; Nallapu, A; Buss, J; Farias, F; Bergmann, K; Bradley, J; Norton, J; Gentsch, J; Wang, F; Davis, AA; Morris, JC; Karch, CM; Perrin, RJ; Benitez, BA; Harari, O;
    2024;  
    PLoS biology;  
    Volume: 22;  
    Issue: 4;  
  36. Cell subtype-specific effects of genetic variation in the Alzheimer's disease brain

    Fujita, M; Gao, Z; Zeng, L; McCabe, C; White, CC; Ng, B; Green, GS; Rozenblatt-Rosen, O; Phillips, D; Amir-Zilberstein, L; Lee, H; Pearse, RV; Khan, A; Vardarajan, BN; Kiryluk, K; Ye, CJ; Klein, H; Wang, G; Regev, A; Habib, N; Schneider, JA; Wang, Y; Young-Pearse, T; Mostafavi, S; Bennett, DA; Menon, V; De Jager, PL;
    2024;  
    Nature Genetics;  
    Volume: 56;  
    Issue: 4;  
  37. Whole genome-wide sequence analysis of long-lived families (Long-Life Family Study) identifies MTUS2 gene associated with late-onset Alzheimer's disease

    Xicota, L; Cosentino, S; Vardarajan, B; Mayeux, R; Perls, TT; Andersen, SL; Zmuda, JM; Thyagarajan, B; Yashin, A; Wojczynski, MK; Krinsky-McHale, S; Handen, BL; Christian, BT; Head, E; Mapstone, ME; Schupf, N; Lee, JH; Barral, S; Long‐Life Family Study (LLFS); Alzheimer's Disease Genetic Consortium (ADGC); Alzheimer's Biomarkers Consortium‐Down Syndrome (ABC‐DS);
    2024;  
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association;  
    Volume: 20;  
    Issue: 4;  
  38. Glial lipid droplets resolve ROS during sleep

    Goodman, LD; Moulton, MJ; Bellen, HJ;
    2024;  
    Nature Neuroscience;  
    Volume: 27;  
    Issue: 4;  
  39. Person-specific differences in ubiquitin-proteasome mediated proteostasis in human neurons

    Hsieh, Y; Augur, ZM; Arbery, M; Ashour, N; Barrett, K; Pearse, RV; Tio, ES; Duong, DM; Felsky, D; De Jager, PL; Bennett, DA; Seyfried, NT; Young-Pearse, TL;
    2024;  
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association;  
    Volume: 20;  
    Issue: 4;  
  40. BHLHE40/41 regulate microglia and peripheral macrophage responses associated with Alzheimer's disease and other disorders of lipid-rich tissues

    Podleśny-Drabiniok, A; Novikova, G; Liu, Y; Dunst, J; Temizer, R; Giannarelli, C; Marro, S; Kreslavsky, T; Marcora, E; Goate, AM;
    2024;  
    Nature Communications;  
    Volume: 15;  
    Issue: 1;  
  41. Risk of Alzheimer's disease is associated with longitudinal changes in plasma biomarkers in the multi-ethnic Washington Heights-Hamilton Heights-Inwood Columbia Aging Project (WHICAP) cohort

    Gu, Y; Honig, LS; Kang, MS; Bahl, A; Sanchez, D; Reyes-Dumeyer, D; Manly, JJ; Dage, JL; Lantigua, RA; Brickman, AM; Vardarajan, BN; Mayeux, R;
    2024;  
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association;  
    Volume: 20;  
    Issue: 3;  
  42. Periodontitis and brain magnetic resonance imaging markers of Alzheimer's disease and cognitive aging

    Rubinstein, T; Brickman, AM; Cheng, B; Burkett, S; Park, H; Annavajhala, MK; Uhlemann, A; Andrews, H; Gutierrez, J; Paster, BJ; Noble, JM; Papapanou, PN;
    2024;  
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association;  
    Volume: 20;  
    Issue: 3;  
  43. Data-Independent Acquisition and Label-Free Quantification for Quantitative Proteomics Analysis of Human Cerebrospinal Fluid

    Makepeace, KAT; Rookyard, AW; Das, L; Vardarajan, BN; Chakrabarty, JK; Jain, A; Kang, MS; Werth, EG; Reyes-Dumeyer, D; Zerlin-Esteves, M; Honig, LS; Mayeux, R; Brown, LM;
    2024;  
    Current Protocols;  
    Volume: 4;  
    Issue: 3;  
  44. Alzheimer's polygenic risk scores are associated with cognitive phenotypes in Down syndrome

    Gorijala, P; Aslam, MM; Dang, LT; Xicota, L; Fernandez, MV; Sung, YJ; Fan, K; Feingold, E; Surace, EI; Chhatwal, JP; Hom, CL; Dominantly Inherited Alzheimer Network (DIAN), the Alzheimer's Disease Neuroimaging Initiative (ADNI); NIA-LOAD family study, for the Alzheimer's Biomarkers Consortium-Down Syndrome (ABC-DS) Investigators; Hartley, SL; Hassenstab, J; Perrin, RJ; Mapstone, M; Zaman, SH; Ances, BM; Kamboh, MI; Lee, JH; Cruchaga, C;
    2024;  
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association;  
    Volume: 20;  
    Issue: 2;  
  45. Longitudinal change in memory performance as a strong endophenotype for Alzheimer's disease

    Archer, DB; Eissman, JM; Mukherjee, S; Lee, ML; Choi, S; Scollard, P; Trittschuh, EH; Mez, JB; Bush, WS; Kunkle, BW; Naj, AC; Gifford, KA; Alzheimer's Disease Neuroimaging Initiative (ADNI); Alzheimer's Disease Genetics Consortium (ADGC); Alzheimer's Disease Sequencing Project (ADSP); Cuccaro, ML; Pericak-Vance, MA; Farrer, LA; Wang, L; Schellenberg, GD; Mayeux, RP; Haines, JL; Jefferson, AL; Kukull, WA; Keene, CD; Saykin, AJ; Thompson, PM; Martin, ER; Bennett, DA; Barnes, LL; Schneider, JA; Crane, PK; Dumitrescu, L; Hohman, TJ;
    2024;  
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association;  
    Volume: 20;  
    Issue: 2;  
  46. Sex-specific genetic architecture of late-life memory performance

    Eissman, JM; Archer, DB; Mukherjee, S; Lee, ML; Choi, S; Scollard, P; Trittschuh, EH; Mez, JB; Bush, WS; Kunkle, BW; Naj, AC; Gifford, KA; Alzheimer's Disease Neuroimaging Initiative (ADNI) | Alzheimer's Disease Genetics Consortium (ADGC) | The Alzheimer's Disease Sequencing Project (ADSP); Cuccaro, ML; Cruchaga, C; Pericak-Vance, MA; Farrer, LA; Wang, L; Schellenberg, GD; Mayeux, RP; Haines, JL; Jefferson, AL; Kukull, WA; Keene, CD; Saykin, AJ; Thompson, PM; Martin, ER; Bennett, DA; Barnes, LL; Schneider, JA; Crane, PK; Hohman, TJ; Dumitrescu, L;
    2024;  
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association;  
    Volume: 20;  
    Issue: 2;  
  47. OXR1 maintains the retromer to delay brain aging under dietary restriction

    Wilson, KA; Bar, S; Dammer, EB; Carrera, EM; Hodge, BA; Hilsabeck, TAU; Bons, J; Brownridge, GW; Beck, JN; Rose, J; Granath-Panelo, M; Nelson, CS; Qi, G; Gerencser, AA; Lan, J; Afenjar, A; Chawla, G; Brem, RB; Campeau, PM; Bellen, HJ; Schilling, B; Seyfried, NT; Ellerby, LM; Kapahi, P;
    2024;  
    Nature Communications;  
    Volume: 15;  
    Issue: 1;  
  48. Proteo-genomics of soluble TREM2 in cerebrospinal fluid provides novel insights and identifies novel modulators for Alzheimer's disease

    Wang, L; Nykänen, N; Western, D; Gorijala, P; Timsina, J; Li, F; Wang, Z; Ali, M; Yang, C; Liu, M; Brock, W; Marquié, M; Boada, M; Alvarez, I; Aguilar, M; Pastor, P; Ruiz, A; Puerta, R; Orellana, A; Rutledge, J; Oh, H; Greicius, MD; Le Guen, Y; Perrin, RJ; Wyss-Coray, T; Jefferson, A; Hohman, TJ; Graff-Radford, N; Mori, H; Goate, A; Levin, J; Sung, YJ; Cruchaga, C;
    2024;  
    Molecular Neurodegeneration;  
    Volume: 19;  
    Issue: 1;  
  49. DNA from multiple viral species is associated with Alzheimer's disease risk

    Tejeda, M; Farrell, J; Zhu, C; Wetzler, L; Lunetta, KL; Bush, WS; Martin, ER; Wang, L; Schellenberg, GD; Pericak-Vance, MA; Haines, JL; Farrer, LA; Sherva, R;
    2024;  
    Alzheimer's & Dementia: The Journal of the Alzheimer's Association;  
    Volume: 20;  
    Issue: 1;  
  50. Effect of altered production and storage of dopamine on development and behavior in C. elegans

    Lee, I; Knickerbocker, AC; Depew, CR; Martin, EL; Dicent, J; Miller, GW; Bucher, ML;
    2024;  
    Frontiers in Toxicology;  
    Volume: 6;  
  51. Epistatic Features and Machine Learning Improve Alzheimer's Disease Risk Prediction Over Polygenic Risk Scores

    Hermes, S; Cady, J; Armentrout, S; O'Connor, J; Holdaway, SC; Cruchaga, C; Wingo, T; Greytak, EM; the Alzheimer’s Disease Neuroimaging Initiative;
    2024;  
    Journal of Alzheimer's disease: JAD;  
    Volume: 99;  
    Issue: 4;  
  52. 2024;  
    Frontiers in Aging Neuroscience;  
    Volume: 16;  
  53. Effects of Menopause and High Fat Diet on Metabolic Outcomes in a Mouse Model of Alzheimer's Disease

    Abi-Ghanem, C; Salinero, AE; Smith, RM; Kelly, RD; Belanger, KM; Richard, RN; Paul, AS; Herzog, AA; Thrasher, CA; Rybka, KA; Riccio, D; Gannon, OJ; Kordit, D; Kyaw, N; Mansour, FM; Groom, E; Brooks, HL; Robison, LS; Pumiglia, K; Zuloaga, DG; Zuloaga, KL;
    2024;  
    Journal of Alzheimer's disease: JAD;  
    Volume: 101;  
    Issue: 4;