ROSMAP DLPFC methylation
Religious Orders Study (ROS) or the Rush Memory and Aging Project (MAP) DLPFC methylation data-set.
Please refer to this document for an overview of the ROSMAP project.
Access
Controlled access. Request data access for ROSMAP on the AD Knowledge Portal; you need a Synapse account. See How to get the data.
| Where | ID | Access | What you get |
|---|---|---|---|
| Synapse | syn3157275 | Controlled | Files described below |
Other Synapse IDs on this page syn69670592 syn69670597 syn69670630 syn69865816
pip install synapseclient
synapse login
synapse get -r syn3157275Contact
Alexandre Pelletier, Jiajun Tao
Study Overview
- Grant number : U01AG046152, R01AG048015, U01AG061356, R01AG15819, U01AG061359
- Publication : PMID: 30084846
- Acknowledgement : Study data were generated from postmortem brain tissue provided by the Religious Orders Study and Rush Memory and Aging Project (ROSMAP) cohort at Rush Alzheimer’s Disease Center, Rush University Medical Center, Chicago.
- Data Citation : Omics data: syn3157275; Genetics data: ng00067
- Genetics Publication : PMID: 40407102
- PI : David A. Bennett (Rush University Medical Center, Chicago, IL, USA)
QTL Analysis
QTL analysis for this dataset is documented in ../../qtl/mQTL/ROSMAP_DLPFC_methylation_qtl.md.
Flagship paper analyses:
- Fine-mapping (fSuSiE/SuSiE-RSS): syn69670592
- Pairwise colocalization (SuSiE-coloc): syn69670597
- AD GWAS–xQTL colocalization results: syn69865816
- AD GWAS–xQTL colocalization models: syn69670630